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DNA (Double Strand) AntibodyNcX DNASerum - DS DNA CTX Test

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DNA (Double Strand) AntibodyNcX DNASerum - DS DNA CTX Test Details in Brief

Also Known As Anti-dsDNA Test, Double-Stranded DNA Antibody Test, dsDNA Antibody EIA
Purpose To diagnose and monitor Systemic Lupus Erythematosus (SLE) and assess lupus disease activity
Preparation No special preparation required
Fasting Not required
Reporting Time Same Day
Cost 1,850

What is an Anti-dsDNA Test?

The anti-double stranded DNA test helps detect antibodies that target the body’s own DNA. These antibodies are commonly seen in Systemic Lupus Erythematosus (SLE), an autoimmune disease where the immune system mistakenly attacks healthy tissues.

This test is highly specific for lupus and is used both for diagnosis and monitoring disease activity, especially when symptoms such as fatigue, joint pain, skin rash, or kidney issues are present.

The test is performed using a simple blood sample, which is analysed in the laboratory by Enzyme Immunoassay (EIA). High antibody levels usually indicate an active phase of lupus or a flare-up, while decreasing levels may suggest improvement or response to treatment.

What Does an Anti-Double Stranded DNA Test Measure?

The test measures the presence and concentration of anti-dsDNA antibodies in your blood. These antibodies are autoantibodies that attack double-stranded DNA, a key component of human cells.

It helps your doctor:

  • Confirm a diagnosis of Systemic Lupus Erythematosus (SLE).
  • Monitor lupus disease activity and treatment response.
  • Detect lupus nephritis, a form of kidney inflammation associated with SLE.
  • Differentiate lupus from other autoimmune conditions.
  • Evaluate the risk of lupus-related complications.

Who Should Consider an Anti-Double Stranded DNA Test?

Your doctor may recommend this test if you have:

  • Symptoms suggestive of lupus, such as fatigue, joint pain, or a butterfly-shaped rash on the face.
  • A positive ANA (antinuclear antibody) test result and need confirmation of lupus.
  • Signs of kidney disease or inflammation.
  • An existing lupus diagnosis requiring disease activity monitoring.

This test is especially useful for patients under treatment for SLE to evaluate therapy effectiveness and detect potential flare-ups.

Why is the Anti-Double Stranded DNA Test Important?

The test plays a critical role in the diagnosis and management of lupus. Anti-dsDNA antibodies are highly specific for SLE, appearing in up to 98 percent of active cases. High antibody levels indicate ongoing inflammation and tissue damage, particularly in organs such as the kidneys.

Early detection helps doctors adjust treatment plans promptly, preventing severe complications like lupus nephritis, which can lead to long-term kidney damage if left untreated.

Anti-Double Stranded DNA Test Booking & Reports – Metropolis Healthcare

How to Book the Anti-Double Stranded DNA Test and Get Your Reports?

  1. Book Online Easily
    Visit the Metropolis Healthcare website or app to schedule your test at a nearby lab or through home collection.
  2. Professional Sample Collection
    A trained phlebotomist collects your blood sample safely and hygienically in a gel vacutainer.
  3. Accredited Testing Process
    The sample is analysed at NABL & CAP accredited laboratories using the Enzyme Immunoassay (EIA) method.
  4. Quick Results
    Reports are ready the same day and can be accessed online or through email and WhatsApp.

Is Home Sample Collection for the Anti-Double Stranded DNA Test Available Near You?

Yes. Home sample collection for the anti-dsDNA test is available. This allows patients to have their blood sample collected safely at home without visiting the lab.

How Long Does It Take to Get an Anti-Double Stranded DNA Test Report?

Reports are generally available the same day after the sample reaches the laboratory.
Note: Reporting time may vary slightly based on your location.

Where Can I See or Get Anti-Double Stranded DNA Test Results?

You can view or download your test report through the Metropolis Healthcare website, app, or directly via email or WhatsApp.

Printed reports can also be collected from your nearest Metropolis lab.

Interpreting Anti-Double Stranded DNA Test Results

What Your Anti-Double Stranded DNA Test Results May Indicate

Parameter

Normal Range

High Values May Indicate

Low/Negative Values May Indicate

Anti-dsDNA Antibodies

Negative < 100 IU/mL

Active lupus, lupus nephritis, or autoimmune disease flare-up

Remission or inactive lupus

 

How Should You Prepare for an Anti-Double Stranded DNA Test?

Minimal preparation is needed before this test:

  • No fasting is required.
  • Inform your doctor about ongoing medications or autoimmune conditions.
  • Provide your full clinical history, especially if you are being treated for lupus or other autoimmune diseases.
  • Drink water as usual before your test.

Diseases That an Anti-Double Stranded DNA Test Can Help Detect

This test helps diagnose and monitor several autoimmune and inflammatory conditions:

  • Systemic Lupus Erythematosus (SLE)
  • Lupus nephritis (kidney inflammation)
  • Mixed connective tissue disease (MCTD)
  • Sjögren’s syndrome
  • Autoimmune hepatitis and chronic infections

Anti-Double Stranded DNA Test Price in Different Cities

The cost of a Anti-Double Stranded DNA Test may vary depending on your location. Here's a table showing the approximate price range for the Anti-Double Stranded DNA Test at Metropolis Healthcare in major Indian cities:

City

Approximate Cost (INR)

Mumbai

₹ 1650 to ₹ 1850

Delhi

₹ 1650 to ₹ 1850

Bengaluru

₹ 1650 to ₹ 1850

Chennai

₹ 1650 to ₹ 1850

The Anti-Double Stranded DNA Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive Anti-Double Stranded DNA Test prices across major cities in India.

 

References

  1. Biesen R., et al. (2011). Anti-dsDNA-NcX ELISA: dsDNA-loaded nucleosomes improve diagnosis and monitoring of lupus disease activity. Arthritis Research & Therapy, 13, R26. PMID: 21375725
  2. Attar S.M., Koshak E.A. (2010). Medical conditions associated with positive anti-double stranded DNA testing. Saudi Medical Journal, 31(7), 781–787. PMID: 20635013
  3. Arbuckle M.R., et al. (2013). Development of autoantibodies before the clinical onset of systemic lupus erythematosus. New England Journal of Medicine, 349(16), 1526–1533. PMID: 14561795
  4. Rahman A., Isenberg D.A. (2008). Systemic lupus erythematosus. New England Journal of Medicine, 358(9), 929–939. PMID: 18305268
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DNA (Double Strand) AntibodyNcX DNASerum - DS DNA CTX Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the DNA (Double Strand) AntibodyNcX DNASerum - DS DNA CTX Test with a clear pricing structure.

The DNA (Double Strand) AntibodyNcX DNASerum - DS DNA CTX Test Price in Mumbai is ₹ 1,850 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

It is used to diagnose and monitor lupus by detecting antibodies that attack the body’s own DNA.

A small blood sample is collected from your vein and analysed using the Enzyme Immunoassay method.

No fasting is required before this test.

It may indicate active lupus or lupus nephritis, especially during a flare-up.

Yes, it helps confirm lupus when combined with clinical symptoms and a positive ANA test.

Occasionally, other autoimmune or liver conditions such as Sjögren’s syndrome or autoimmune hepatitis may cause a positive result.

Lupus patients may be advised to repeat this test regularly to monitor disease activity and treatment response.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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