Cyclosporine, Blood By LC MSMS Test
₹3050
₹3050
Cyclosporine is a lipophilic polypeptide used to prevent rejection after solid organ transplantation; it suppresses T-cell activation by inhibiting calcineurin to decrease interleukin-2 (IL-2) production. There is substantial interpatient variability in absorption, half-life, and other pharmacokinetic parameters.
Cyclosporine is a immunosuppressant and requires therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations.
This test is done for calculation of amount of drug cyclosporine in your blood
Cyclosporine is a lipophilic polypeptide used to prevent rejection after solid organ transplantation; it suppresses T-cell activation by inhibiting calcineurin to decrease interleukin-2 (IL-2) production. There is substantial interpatient variability in absorption, half-life, and other pharmacokinetic parameters. It is known for many drug interactions, including increased neuro- and nephrotoxicity when coadministered with antibiotics, antifungals, or other immunosuppressants. It has a narrow therapeutic range with frequent adverse effects making therapeutic drug monitoring essential.
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