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Cardiolipin ACL-IgG Antibody Test
Also known as: Cardiolipin ACL-IgG Antibody Serum
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
Cardiolipin ACL-IgG Antibody Serum Details in Brief
| Also Known As | Anti-Cardiolipin IgG Test, ACL-IgG Antibody Test, Antiphospholipid Antibody Test |
|---|---|
| Purpose | Diagnoses Antiphospholipid Syndrome (APS), investigates recurrent pregnancy loss, unexplained blood clots, or autoimmune disorders like lupus |
| Preparation | No special preparation required |
| Fasting | Fasting not required |
| Reporting Time | Same day |
| Cost | 1,040 |
What is a Cardiolipin ACL-IgG Antibody Test?
The Cardiolipin ACL-IgG Antibody Test is a blood test that detects IgG antibodies targeting cardiolipin, a type of phospholipid found in cell membranes. These antibodies are produced by the immune system when it mistakenly attacks the body’s own cells, leading to autoimmune and clotting disorders.
Doctors use this test to help diagnose Antiphospholipid Syndrome (APS), a condition associated with abnormal blood clotting, pregnancy complications, and recurrent miscarriages. It is also useful in evaluating patients with Systemic Lupus Erythematosus (SLE) and other autoimmune diseases.
The test requires a small blood sample drawn from a vein and is performed using the Fluorescence Immunoassay (FIA) method for high sensitivity and accuracy.
What Does a Cardiolipin ACL-IgG Antibody Test Measure?
This test measures the amount of IgG antibodies that react against cardiolipin. Elevated levels may indicate an increased risk of abnormal clot formation or autoimmune activity.
It helps assess:
- Autoimmune Response: Detects antibodies against cardiolipin, suggesting an immune system malfunction.
- Blood Clotting Risk: Identifies patients at risk of deep vein thrombosis, stroke, or pulmonary embolism.
- Pregnancy Complications: Helps explain recurrent miscarriages or preeclampsia due to blood flow disturbances in the placenta.
- Autoimmune Disease Activity: Supports diagnosis and monitoring of lupus and related disorders.
- Treatment Monitoring: Used to track response to anticoagulant or immunosuppressive therapy in APS patients.
Cardiolipin ACL-IgG Antibody Test: Who Needs It and Why It’s Done
What Symptoms May Call for a Cardiolipin ACL-IgG Antibody Test?
Your doctor may recommend this test if you have:
- Repeated miscarriages or stillbirths
- Unexplained blood clots in the legs, lungs, or brain
- Early-onset stroke or heart attack without known cause
- Prolonged clotting time on blood tests
- Symptoms of lupus or another autoimmune disorder
Who Should Get a Cardiolipin ACL-IgG Antibody Test?
This test is especially important for:
- Women with a history of recurrent pregnancy loss
- Individuals with deep vein thrombosis (DVT), stroke, or pulmonary embolism without clear reason
- Patients diagnosed with or suspected of Antiphospholipid Syndrome (APS)
- People with autoimmune disorders such as lupus (SLE)
- Patients being evaluated for unexplained infertility or neurological symptoms related to clotting
Why is a Cardiolipin ACL-IgG Antibody Test Done?
This test helps determine whether your body is producing antibodies that cause abnormal blood clotting or immune reactions. It plays a key role in diagnosing APS, autoimmune disorders, and pregnancy complications caused by these antibodies.
Importance of a Cardiolipin ACL-IgG Antibody Test
The Cardiolipin ACL-IgG Antibody Test is essential for early detection and management of autoimmune clotting disorders. Identifying these antibodies helps prevent serious complications such as stroke, miscarriage, and deep vein thrombosis. A positive result can guide your doctor in starting preventive treatments like anticoagulant therapy and monitoring your risk of clot-related conditions over time.
Cardiolipin ACL-IgG Antibody Test Booking & Reports – Metropolis Healthcare
How to Book the Cardiolipin ACL-IgG Antibody Test and Get Your Reports?
- Simple Online Booking
You can easily book the Cardiolipin ACL-IgG Antibody Test through the Metropolis Healthcare App or website. Choose your preferred time slot and opt for home sample collection or visit your nearest Metropolis Lab. - Safe Home Sample Collection
Our trained phlebotomists collect your blood sample at home following strict safety and hygiene protocols. - Sample Tracking Updates
Track your sample status directly through the Metropolis Healthcare App or website. - Accurate Laboratory Testing
Your sample is analysed at NABL & CAP accredited Metropolis Labs using the Fluorescence Immunoassay (FIA) method for precise and reliable results. - Quick & Easy Reports
Get your reports conveniently through email, WhatsApp, or download them from the Metropolis Healthcare website or app.
Is Home Sample Collection for Cardiolipin ACL-IgG Antibody Test Available Near You?
Yes. Metropolis Healthcare offers home sample collection for this test, ensuring comfort and convenience. Our expert phlebotomists collect your sample at a time that suits you, reducing the need for lab visits.
How Long Does It Take to Get a Cardiolipin ACL-IgG Antibody Test Report?
Reports are usually available on the same day once your sample reaches the lab.
Note: Reporting time may vary depending on your location.
Where Can I See or Get Cardiolipin ACL-IgG Antibody Test Results?
- You can easily access your test results through the Metropolis Healthcare App or website.
- Reports are also shared via email or WhatsApp,
- and you can collect a physical copy from the nearest Metropolis Lab.
Interpreting Cardiolipin ACL-IgG Antibody Test Results
What Your Cardiolipin ACL-IgG Antibody Test Results May Indicate
|
Parameter |
Normal Range |
Result Interpretation |
|
Cardiolipin Antibody ACL-IgG |
Negative: <15 GPL U/mL |
Positive results suggest Antiphospholipid Syndrome (APS), Systemic Lupus Erythematosus (SLE), or increased risk of thrombosis and pregnancy loss |
Understanding Abnormal Cardiolipin ACL-IgG Antibody Test Results by Parameter
|
Parameter |
High Values May Indicate |
Low/Normal Values May Indicate |
|
Cardiolipin Antibody ACL-IgG |
Antiphospholipid Syndrome (APS), recurrent miscarriages, lupus, thrombosis, stroke, autoimmune inflammation |
Normal immune function, low risk of clot-related autoimmune disorders |
How Should You Prepare for a Cardiolipin ACL-IgG Antibody Test?
The Cardiolipin ACL-IgG Antibody Test is simple and requires minimal preparation:
- No fasting required: You can eat and drink normally before the test.
- Medication review: Inform your doctor about any anticoagulants or immunosuppressive drugs you are taking, as they may affect the results.
- Hydration: Drink plenty of water before your test for easy blood collection.
- Health condition: Avoid testing during acute infection unless directed by your doctor.
- Relaxation: Try to stay calm and well-rested before the test.
How Is a Cardiolipin ACL-IgG Antibody Test Done? (Step-by-Step Procedure)
The Cardiolipin ACL-IgG Antibody Test is performed through a simple blood collection process:
- Preparation: A tourniquet is tied around your upper arm to make veins more visible.
- Cleaning: The puncture site is cleaned with antiseptic.
- Sample Collection: About 3 ml of blood is drawn from a vein into a gel vacutainer.
- Completion: The needle is removed, and a small bandage is applied.
- Processing: The sample is analysed using the Fluorescence Immunoassay (FIA) method to detect IgG antibodies against cardiolipin.
Conditions That May Affect Cardiolipin ACL-IgG Antibody Test Accuracy
Several factors can temporarily influence your test results:
- Recent infections or vaccinations may cause transient antibody elevation.
- Certain autoimmune flare-ups can affect antibody levels.
- Pregnancy may alter immune responses and impact results.
- Repeat testing after 12 weeks is recommended for confirming persistent positivity, essential for APS diagnosis.
Diseases That a Cardiolipin ACL-IgG Antibody Test Can Help Detect
This test helps in diagnosing and managing:
- Antiphospholipid Syndrome (APS)
- Systemic Lupus Erythematosus (SLE)
- Recurrent miscarriages or stillbirths
- Deep Vein Thrombosis (DVT)
- Stroke or Transient Ischaemic Attack (TIA)
- Autoimmune coagulation disorders
- Pregnancy complications related to abnormal clotting
Cardiolipin ACL-IgG Antibody Test Price in Different Cities
The cost of a Cardiolipin ACL-IgG Antibody Test may vary depending on your location. Here's a table showing the approximate price range for the Cardiolipin ACL-IgG Antibody Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 1,000 to ₹ 1,100 |
|
|
₹ 1,000 to ₹ 1,100 |
|
|
₹ 1,000 to ₹ 1,100 |
|
|
₹ 1,000 to ₹ 1,100 |
The Cardiolipin ACL-IgG Antibody Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive Cardiolipin ACL-IgG Antibody Test prices across major cities in India.
References
- Miyakis S., et al. (2006). International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). Journal of Thrombosis and Haemostasis, 4(2), 295–306. PMID: 16420554
- Bertolaccini M.L., et al. (2010). Laboratory testing for antiphospholipid antibodies: current and emerging issues. Pathophysiology of Haemostasis and Thrombosis, 37(2–4), 49–57. PMID: 21135521
- Willis R., et al. (2011). Pathophysiology of the antiphospholipid antibody syndrome. Autoimmunity, 44(6), 433–438. PMID: 21495932
- Cervera R., et al. (2009). Morbidity and mortality in the antiphospholipid syndrome during a 10-year period. Annals of the Rheumatic Diseases, 68(9), 1428–1432. PMID: 18713794
- Devreese K.M.J., et al. (2020). Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the ISTH. Journal of Thrombosis and Haemostasis, 18(11), 2828–2839. PMID: 32866984
Cardiolipin ACL-IgG Antibody Serum Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Cardiolipin ACL-IgG Antibody Serum with a clear pricing structure.
The Cardiolipin ACL-IgG Antibody Serum Price in Bangalore is ₹ 1,040 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
A positive result suggests the presence of antiphospholipid antibodies associated with Antiphospholipid Syndrome (APS) or lupus, increasing the risk of clotting or pregnancy complications.
Fasting is not required. You can eat and drink normally before the test.
Not by itself. APS diagnosis requires repeat positive results at least 12 weeks apart, along with clinical symptoms such as clotting or pregnancy loss.
Blood thinners or immunosuppressive medications may alter antibody levels. Inform your doctor before the test.
The risks are minimal and similar to any routine blood draw, such as mild bruising or temporary discomfort.
Your doctor may recommend repeating the test after 12 weeks if results are positive, to confirm persistence of antibodies for APS diagnosis.
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