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Cancer marker profile (Neuroendocrine tumors)

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Overview

Neuroendocrine tumours are rare and can occur anywhere in the body. Most common sites are lungs, appendix, small intestine, rectum and pancreas. These tumours often cause abnormal production of hormones impacting important functions. The diagnosis or initial screening is done by certain cancer marker tests. Cancer markers or tumour markers are proteins produced by the normal cells as well as cancer cells, but are produced in higher levels by the cancer cells. Cancer marker profile (Neuroendocrine tumors) consists of tests to measure the levels of tumour markers in the blood. This profile test may be useful in the screening of certain endocrine cancers and decide the treatment prognosis. Diagnosis or treatment of neuroendocrine tumours depend on the type, location and hormone production.

WRITTEN BY: Dr.Shibani R Medical Writer, Medical Affairs

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Cancer marker profile (Neuroendocrine tumors) Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Cancer marker profile (Neuroendocrine tumors) with a clear pricing structure.

The Cancer marker profile (Neuroendocrine tumors) Price in Mumbai is ₹ 6,570 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The Cancer marker profile (Neuroendocrine tumors) measures the Chromogranin A, and NSE levels in the blood.

  • This test is useful for the screening of neuroendocrine tumors. It should however not be used in isolation for the diagnosis of tumours.
  • The profile tests can be used for monitoring treatment and relapse in patients with hormone dependent tumours.
  • The test may be used as a prognostic marker for survival following certain surgeries.
  •  To know the stage of cancer as well as the metastasis status
  • The test can help detect recurrence, metastasis and residual cancer.

Neuroendocrine tumours may not produce any symptoms in the initial stages. Depending on the size of the tumour, its location and hormonal activity it may produce the following general signs and symptoms:

  • Headache [radiating or non-radiating]
  • Pain, numbness and muscle weakness [due to facial nerve impingement]
  • Nausea, vomiting
  • Seizures
  • Diarrhoea
  • Skin flushing
  • Dizziness

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

 

Chromogranin A

The levels are elevated in gastrinoma, pheochromocytoma, carcinoid tumors, and medullary carcinoma of the thyroid.

Chromogranin A is not a diagnostic test for endocrine tumors. It can be elevated in patients with renal failure and in patients of atrophic chronic gastritis.

In some cases, levels may also be elevated in healthy subjects.

 

NSE-Neuron Specific Enolase Test

Increased NSE levels may occur in malignant neuroendocrine diseases like carcinoid tumour, medullary thyroid carcinoma, Merkel cell tumour of the skin, carcinoma of pancreas & Adrenal medulla as well in certain cases of Benign Lung diseases.

Increased levels may at times also occur due to epilepsy, encephalitis and other brain disorders.

  • Endocrine cancer tests
  • NSE test
  • Chromogranin A test

Human Chromogranin A is a tumour marker used to differentiate between endocrine and non-endocrine tumors. Chromogranin A is not a diagnostic test for endocrine tumors. It can be elevated even in patients with renal failure and in patients of atrophic chronic gastritis.

NSE is an isoenzyme found in neuronal and neuroendocrine tissues. Its levels in the blood are normally negligible. NSE test is used for monitoring disease progression & therapy in patients with Small cell lung carcinoma & neuroendocrine tumors.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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