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Calprotectin Stool Test
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Blood
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Calprotectin Stool Test Overview
Calprotectin Stool test measures the amount of protein calprotectin in your stool
Stool calprotectin is a biomarker used to assess inflammation in the digestive system. Calprotectin is a protein that is released by white blood cells, particularly neutrophils, in response to inflammation.
When there is inflammation in the digestive system, calprotectin is released into the intestinal tract and ultimately ends up in the stool. By measuring the level of calprotectin in a stool sample, healthcare providers can determine the presence and severity of inflammation in the digestive system.
Associated Tests:
Coeliac Disease Profile-2 Comprehensive
Celiac Disease Profile
Coeliac disease Profile-1
IBD Profile
IBD Profile - 2
The calprotectin stool test, also known as the faecal calprotectin test, is a noninvasive diagnostic tool designed to detect and measure the levels of calprotectin in a stool sample. Calprotectin is a protein produced by white blood cells called neutrophils. This test plays a crucial role in identifying and monitoring inflammation in the gastrointestinal tract, particularly in distinguishing between inflammatory bowel diseases (IBD) and noninflammatory bowel conditions such as irritable bowel syndrome (IBS).
Written by: Supriya Kulkarni, Lead-Content & Training
Reasons for Undergoing the Calprotectin Stool Test
The calprotectin stool test is typically recommended for several reasons:
- Diagnosis of Inflammatory Bowel Disease (IBD): The test helps differentiate between IBD (such as Crohn's disease and ulcerative colitis) and noninflammatory conditions like irritable bowel syndrome (IBS).
- Monitoring IBD: The test is used to assess the effectiveness of treatment and determine the severity of IBD flares.
- Symptom Evaluation: Patients experiencing symptoms such as watery or bloody diarrhoea, abdominal cramps, fever, unintentional weight loss, and rectal bleeding may undergo this test to identify the underlying cause of these symptoms.
- Excluding Other Conditions: The test can help rule out other gastrointestinal conditions like bacterial, viral, or parasitic infections; colorectal or intestinal cancer; and other inflammatory conditions.
List of Parameters Considered During the Calprotectin Stool Test
The calprotectin stool test measures the level of calprotectin in the stool sample, expressed in micrograms per gram (mcg/g) of stool:
- Low levels (<100 mcg/g): Very low IBD risk (<2%); consider IBS or viral infections.
- Intermediate levels (100-250 mcg/g): Moderate IBD risk (~12%); further testing recommended after withholding NSAIDs/PPIs for 4-6 weeks.
- High levels (>250 mcg/g): High IBD risk (~46%); urgent gastroenterology referral advised.
Calprotectin Stool Test Preparation
Preparing for a calprotectin stool test is relatively straightforward:
- Collection Kit: Use the clean container or kit provided, following instructions carefully.
- Avoid Mixing: Ensure the stool does not mix with urine, toilet paper, or toilet water.
- Labelling: Label the container with your name, collection date, and time.
- Collection Method: Use a clean, dry container or special wrap to catch the stool; seal tightly.
- Hygiene: Wash hands thoroughly after collection.
- Dietary Notes: No fasting is needed; avoid NSAIDs/PPIs for 4-6 weeks if possible.
Calprotectin Stool Test Results & Interpretation
The results of the calprotectin stool test are interpreted based on the levels of calprotectin found in the stool:
- Low Risk (<100 mcg/g): Very low IBD risk; consider alternative diagnoses. Colonoscopy is usually unnecessary unless strong suspicion exists.
- Intermediate Risk (100-250 mcg/g): Repeat testing if NSAIDs/PPIs are withheld. Persistent levels may warrant colonoscopy referral.
- High Risk (>250 mcg/g): High IBD risk; urgent gastroenterology referral or acute care may be needed.
Home Collection for Calprotectin Stool Test
Home collection for the calprotectin stool test offers a convenient solution for individuals to get tested without visiting a clinic. With Metropolis Healthcare's lab services, a trained phlebotomist comes to your doorstep to collect the stool sample. This service ensures comfort and safety while maintaining high standards of sample handling and testing accuracy.
Calprotectin Stool Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Calprotectin Stool Test with a clear pricing structure.
The Calprotectin Stool Test Price in Mumbai is ₹ 3,200 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
To detect inflammation in the intestines; to distinguish between inflammatory bowel disease (IBD) and non-inflammatory bowel conditions; to monitor for a condition called “inflammatory bowel disease (IBD)”.
Your doctor may recommend Calprotectin stool test for you when you show symptoms like:
- Bloody or watery diarrhoea
- Abdominal cramps
- Fever lasting for than few days
Calprotectin is a protein released by the blood cells of the body’s defence system-WBCs, especially neutrophils. When there is an inflammation in the body, especially the gastrointestinal tract, the neutrophils get transported to the concerned site of action and release calprotectin, which then gets excreted in the faeces. Calprotectin stool test assesses the presence of any inflammatory reactions taking place in the intestine.
The Stool Calprotectin test helps in:
- Assessment of inflammation in the digestive system
- Diagnosis of inflammatory bowel diseases, specifically Crohn’s disease and ulcerative colitis
- Differentiation of IBD from irritable bowel syndrome
- Monitoring and managing digestive system inflammation
The stool calprotectin test is a diagnostic test that measures the level of calprotectin in the stool.
An abnormal result on a Calprotectin Stool test may indicate the presence of inflammation in the digestive system, particularly in the intestines. It may be indicative of inflammatory bowel disease (IBD), Crohn's disease, ulcerative colitis or other inflammatory conditions.
The stool calprotectin test is a simple and non-invasive diagnostic test that can be performed at home or in a medical laboratory. 100 gms of stool in a sterile leakproof container is collected. The history of medicines needs to be reported. The sample should be collected from the first bowel movement of the day and be free of urine or toilet paper
The test is relatively simple and straightforward, and in most cases, no special preparation is required. However, it is important to follow the instructions provided by your healthcare provider or the testing facility to ensure that the sample is properly collected and handled.
Some of the symptoms or conditions that may warrant a Calprotectin Stool test include:
- Persistent diarrhea: If you have had diarrhea that lasts for several days or longer, your healthcare provider may order a Calprotectin Stool test to help determine the cause of your symptoms.
- Abdominal pain or cramping: If you experience frequent or severe abdominal pain or cramping, especially if it is accompanied by changes in bowel habits, a Calprotectin Stool test may be ordered to help identify the cause.
- Blood in the stool: If you notice blood in your stool, your healthcare provider may order a Calprotectin Stool test to help determine whether inflammation in the digestive tract may be contributing to your symptoms.
- Inflammatory bowel disease (IBD): If you have been diagnosed with IBD, such as Crohn's disease or ulcerative colitis, a Calprotectin Stool test may be used to monitor the severity of the inflammation and the effectiveness of treatment.
- Irritable bowel syndrome (IBS): While IBS does not typically cause inflammation in the digestive tract, some healthcare providers may order a Calprotectin Stool test to help rule out other potential causes of symptoms.
Fecal Calprotectin test
Fecal Calprotectin assay
Home collection for the Calprotectin Stool Test offers a convenient solution for individuals to get tested without visiting a clinic. With Metropolis Healthcare's lab services, a trained phlebotomist comes to your doorstep to collect the stool sample.
The Calprotectin Stool Test is used to diagnose and monitor inflammatory bowel disease (IBD), distinguish between IBD and irritable bowel syndrome (IBS), evaluate gastrointestinal symptoms, and assess the effectiveness of treatment and severity of IBD flares.
The normal range for the Calprotectin Stool Test is categorised as low risk (<100 mcg/g), intermediate risk (100-250 mcg/g), and high risk (>250 mcg/g).
Anyone experiencing gastrointestinal symptoms or suspected of having inflammatory bowel disease (IBD) or other inflammatory bowel conditions is eligible for the Calprotectin Stool Test.
The Calprotectin Stool Test is non-invasive, helps differentiate between IBD and non-inflammatory conditions, monitors treatment effectiveness, and reduces the need for more invasive tests.
The frequency of the Calprotectin Stool Test depends on your individual health condition and your doctor's recommendation. It is typically used for diagnosing and monitoring IBD, so the frequency may vary based on the severity of your condition and response to treatment.
There is no specific time requirement for the Calprotectin Stool Test. You can collect the stool sample at any time of the day, following the instructions provided by your healthcare provider or the home collection kit.
No, fasting is not required for the Calprotectin Stool Test.
Apart from avoiding NSAIDs and PPIs, there are no specific precautions to be taken before the Calprotectin Stool Test. However, it is essential to follow the instructions provided for collecting the stool sample to ensure accurate results.
The Calprotectin Stool Test measures the level of calprotectin in the stool sample, expressed in micrograms per gram (mcg/g) of stool.
The Calprotectin Stool Test involves collecting a stool sample in a clean container provided by your healthcare provider or home collection kit. The sample is then sent to a laboratory for analysis.
The Calprotectin Stool Test should be done when recommended by your doctor, typically when you are experiencing gastrointestinal symptoms or suspected of having inflammatory bowel disease (IBD) or other inflammatory bowel conditions.
The Calprotectin Stool Test is considered positive when the levels of calprotectin in the stool sample are elevated. Levels above 250 mcg/g are considered high-risk and may indicate the presence of inflammatory bowel disease (IBD).
The Calprotectin Stool Test itself takes only a few minutes to collect the stool sample. However, the time required for the laboratory analysis may vary depending on the facility and workload.
The time required to receive the Calprotectin Stool Test reports may vary depending on the lab. Typically, results are available within 24 hours based on the day/time when the sample was collected and processed.
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