Tacrolimus-by LCMS Test in Bhandup - Metropolis Healthcare
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Tacrolimus-by LCMS Test

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Test Overview

Tacrolimus (Prograf) is a macrolide antibiotic derived from the fungus Streptomyces tsukubaenesis.

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Frequently Asked Questions

Tacrolimus is a immunosuppressant and requires therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations.

This test is done for calculation of amount of drug tacrolimus in your blood.

Tacrolimus (Prograf) is a macrolide antibiotic derived from the fungus Streptomyces tsukubaenesis. Tacrolimus is metabolized by CYP3A4; thus, its concentration is affected by drugs that inhibit (calcium channel blockers, antifungal agents, some antibiotics, grapefruit juice) or induce (anticonvulsants, rifampin) this enzyme. Tacrolimus has a narrow therapeutic range and adverse effects are common, particularly at high dose and concentrations, making therapeutic drug monitoring essential.

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