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Anti Smooth Muscle Antibody ASMA Test
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
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Anti Smooth Muscle Antibody ASMA Test Details in Brief
| Also Known As | Anti-Smooth Muscle Antibody Test, Smooth Muscle Antibody Test |
|---|---|
| Purpose | Helps diagnose autoimmune hepatitis and differentiate autoimmune liver disease from other liver conditions |
| Preparation | No specific preparation required |
| Fasting | Fasting not required |
| Reporting Time | Same Day |
| Cost | 2,235 |
What is an ASMA Test?
The ASMA Test (Anti-Smooth Muscle Antibody Test) is a blood test used to detect autoantibodies that mistakenly attack the body’s own smooth muscle cells, particularly in the liver. These antibodies are often present in people with Autoimmune Hepatitis (AIH), a condition where the immune system attacks healthy liver tissue, leading to inflammation, scarring (cirrhosis), and impaired liver function.
This test helps your doctor determine if your liver problems are caused by autoimmune reactions rather than infections, alcohol use, or medications. It is also useful in evaluating chronic liver disease and overlap syndromes where multiple autoimmune liver conditions coexist.
The test is performed on a serum sample collected from your blood.
What Does an ASMA Test Measure?
The ASMA Test measures the presence of anti-smooth muscle antibodies (ASMA) in your bloodstream. These are immune proteins that target smooth muscle fibres found in organs such as the liver, stomach, and blood vessels.
It helps your doctor to:
- Detect autoimmune hepatitis (Type 1), the most common autoimmune liver disorder
- Differentiate autoimmune liver disease from viral or alcohol-related liver conditions
- Support the diagnosis of chronic active hepatitis and primary biliary cirrhosis
- Assess disease activity and monitor response to treatment in autoimmune hepatitis
- Identify autoimmune triggers in patients with unexplained liver dysfunction
ASMA Test: Who Needs It and Why It’s Done
What Symptoms May Call for an ASMA Test?
Your doctor may recommend an ASMA Test if you have symptoms suggestive of liver disease, such as:
- Yellowing of the skin or eyes (jaundice)
- Abdominal pain or swelling
- Persistent fatigue or weakness
- Itchy skin or dark-coloured urine
- Pale stools
- Nausea or loss of appetite
Who Should Get an ASMA Test?
You may need this test if you are:
- Showing signs of chronic liver disease without a clear cause
- Suspected to have autoimmune hepatitis (AIH)
- Undergoing evaluation for liver cirrhosis or autoimmune liver overlap syndromes
- Experiencing unexplained elevated liver enzymes (ALT, AST)
- Being monitored for autoimmune disease progression or treatment response
Why is an ASMA Test Done?
The test is performed to detect antibodies associated with autoimmune liver disease, particularly autoimmune hepatitis. Identifying these antibodies helps your doctor diagnose the condition early, differentiate it from other liver disorders, and begin appropriate treatment to prevent long-term liver damage.
Importance of an ASMA Test
An ASMA Test plays a vital role in evaluating the autoimmune causes of liver dysfunction. Detecting these antibodies helps doctors confirm autoimmune hepatitis early, even before significant liver damage occurs. The test also helps guide treatment decisions, track disease progression, and monitor response to therapy in diagnosed patients.
By confirming autoimmune liver activity, the test ensures you receive timely medical care to prevent complications such as cirrhosis or liver failure.
ASMA Test Booking & Reports – Metropolis Healthcare
How to Book the ASMA Test and Get Your Reports?
- Simple Online Booking
You can book the ASMA Test through the Metropolis Healthcare website or mobile app. Choose your preferred time for home sample collection or visit the nearest Metropolis Lab. - Safe Home Sample Collection
Our trained phlebotomists visit your home at your chosen time, following strict hygiene and safety protocols. - Sample Tracking Updates
You can track your sample and test status directly through the Metropolis Healthcare website or app. - Accurate Laboratory Testing
The sample is processed in NABL & CAP accredited laboratories using the Immunofluorescence Assay (IFA) method to ensure high accuracy. - Quick & Easy Reports
Reports are delivered on the same day via email, WhatsApp, or the Metropolis Healthcare app.
Is Home Sample Collection for ASMA Test Available Near You?
Yes, Metropolis Healthcare offers convenient home sample collection for the ASMA Test. Our expert technicians collect your blood sample safely from your home, ensuring a comfortable experience and reliable reporting without visiting a lab.
How Long Does It Take to Get an ASMA Test Report?
Reports are usually available on the same day once your sample reaches the laboratory.
Note: Reporting time and cost may vary based on your location.
Where Can I See or Get ASMA Test Results?
You can access your ASMA Test results through the Metropolis Healthcare website or mobile app. Reports are also shared via email or WhatsApp, and printed copies can be collected from your nearest Metropolis lab.
Interpreting ASMA Test Results
What Your ASMA Test Results May Indicate
|
Parameter |
Biological Reference Interval |
Positive (Reactive) May Indicate |
Negative (Non-Reactive) May Indicate |
|
ASMA (Smooth Muscle Antibody) |
Negative |
Autoimmune Hepatitis (Type 1), Chronic Active Hepatitis, Liver Cirrhosis |
No detectable antibodies; autoimmune liver disease unlikely |
Understanding Abnormal ASMA Test Results by Parameter
|
Parameter |
High Value Interpretation |
Low/Negative Value Interpretation |
|
ASMA (Smooth Muscle Antibody) |
Suggests autoimmune liver disease such as Autoimmune Hepatitis or Primary Biliary Cirrhosis |
Indicates absence of autoimmune antibodies; other causes of liver disease should be evaluated |
How Should You Prepare for an ASMA Test?
The ASMA Test requires minimal preparation. To ensure accurate results:
- No fasting required – you can eat and drink normally.
- Inform your doctor about any medications or supplements you are taking.
- Avoid high-dose biotin supplements (more than 5 mg per day) at least 8 hours before testing.
- Provide full medical history related to your liver health and current symptoms.
- Stay hydrated before your appointment.
How Is an ASMA Test Done? (Step-by-Step Procedure)
The ASMA Test involves a straightforward blood collection process:
- Preparation: A tourniquet is tied around your upper arm to make veins more visible.
- Cleaning: The puncture site is cleaned with antiseptic.
- Sample Collection: A sterile needle is inserted to draw around 3 ml of blood into a gel vacutainer.
- Completion: The needle is removed and a small bandage is applied.
- Processing: The blood sample is analysed using Immunofluorescence Assay (IFA) to detect the presence of anti-smooth muscle antibodies.
Conditions That May Affect ASMA Test Accuracy
Some factors can influence your test results:
- Medications such as corticosteroids or immunosuppressants may alter antibody levels.
- Viral infections (e.g., Epstein–Barr virus, Hepatitis viruses) can cause false-positive results.
- Other autoimmune diseases such as lupus or thyroid disorders may cross-react.
- Severe liver inflammation or cirrhosis can modify antibody expression.
- Testing too early or late during disease progression can affect detection levels.
Diseases That an ASMA Test Can Help Detect
The ASMA Test helps detect and support diagnosis for:
- Autoimmune Hepatitis (Type 1)
- Primary Biliary Cirrhosis
- Chronic Active Hepatitis
- Liver Cirrhosis (Autoimmune or Alcohol-related)
- Overlap Syndromes (Autoimmune Hepatitis with PBC or PSC)
Other Autoimmune Conditions likelupus, viral infections, and certain cancers
ASMA Test Price in Different Cities
The cost of a ASMA Test may vary depending on your location. Here's a table showing the approximate price range for the ASMA Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 1900 to ₹ 2300 |
|
|
₹ 1900 to ₹ 2300 |
|
|
₹ 1900 to ₹ 2300 |
|
|
₹ 1900 to ₹ 2300 |
The ASMA Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive ASMA Test prices across major cities in India.
References
- Liberal R., & Mieli-Vergani G. (2013). Pathogenesis of autoimmune hepatitis. Seminars in Liver Disease, 34(3), 296–305. PMID: 25260366
- Czaja A.J. (2014). Autoimmune hepatitis—approach to diagnosis and treatment. Hepatology, 59(2), 948–958. PMID: 24122855
- Vergani D., & Mieli-Vergani G. (2018). Autoimmune hepatitis in adults and children: Pathogenesis and diagnosis. Clinical Liver Disease, 22(2), 389–402. PMID: 29671556
- Krawitt E.L. (2006). Autoimmune hepatitis. New England Journal of Medicine, 354(1), 54–66. PMID: 16407508
- Lohse A.W., & Mieli-Vergani G. (2011). Autoimmune hepatitis. Journal of Hepatology, 55(1), 171–182. PMID: 21238516
Anti Smooth Muscle Antibody ASMA Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Anti Smooth Muscle Antibody ASMA Test with a clear pricing structure.
The Anti Smooth Muscle Antibody ASMA Test Price in Mumbai is ₹ 2,235 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
It detects antibodies that attack smooth muscle cells, mainly in the liver, helping diagnose autoimmune hepatitis.
No, fasting is not required. You can eat and drink normally before the test.
A positive result suggests autoimmune hepatitis or other autoimmune liver conditions.
Rarely, low antibody levels may appear in healthy people or other conditions, so results must be interpreted with clinical findings.
A small blood sample is collected from a vein and tested using Immunofluorescence Assay (IFA).
Your doctor may order additional tests like ANA, AMA, or LKM antibodies to determine the cause.
Tests like SLA Blot and Autoimmune Hepatitis Profile may be recommended for confirmation.
Reports are usually available on the same day by 9:00 PM.
Yes, viral infections like hepatitis or Epstein–Barr virus can cause false positives.
Yes, Metropolis Healthcare provides safe and convenient home sample collection for this test.
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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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