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Arthritis Profile

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Arthritis Profile Overview

Arthritis is an inflammatory condition of bones and joints characterized by severe pain and joint swelling. Many autoimmune disorders can cause arthritis e.g. SLE, Rheumatoid arthritis, vasculitis etc. It can also be associated with non-autoimmune conditions like gout. An arthritis profile is a series of blood tests performed to assess the levels of various inflammatory and routine parameters in the blood that may aid the diagnosis of arthritis.

Written by: Dr.Shibani R. Medical Writer, Medical Affairs

Reasons for Undergoing the Arthritis Profile Test 

Arthritis is a common condition that affects millions of people worldwide, causing joint pain, stiffness, and reduced mobility. Diagnosing and managing this condition early is crucial to improve the quality of life and preventing further complications. One valuable tool in achieving this is the arthritis profile test—a comprehensive blood test designed to assess various factors related to arthritis. Below are the key reasons why this blood test for arthritis is crucial in the diagnosis, treatment, and management of arthritis: 

  • Early detection and diagnosis of arthritis, even before symptoms become apparent 

  • Identification of the specific type of arthritis, such as rheumatoid arthritis or osteoarthritis 

  • Assessment of the severity of the arthritis condition 

  • Planning and monitoring of treatment effectiveness 

  • Evaluation of risk in individuals with a family history of arthritis 

  • Confirmation of arthritis in patients experiencing symptoms like joint pain, stiffness, or swelling 

List of Parameters Considered during the Arthritis Profile Test 

To manage arthritis effectively, it is essential to understand the underlying factors that contribute to its progression. One of the most comprehensive ways to assess these factors is through an arthritis profile blood test. This test includes a variety of important parameters that offer a detailed view of the individual’s health, particularly in relation to their arthritis. These parameters help in diagnosing, monitoring, and managing the condition, providing insight into inflammation, bone health, and potential autoimmune responses. The key components of an arthritis profile blood test include: 

  • Complete Blood Picture (CBP) or Complete Blood Count (CBC): Assesses white blood cells, red blood cells, platelets, and haemoglobin levels to identify infections, anaemia, or blood disorders. 

  • Erythrocyte Sedimentation Rate (ESR): Measures the rate at which red blood cells settle, indicating inflammation levels in the body. 

  • C-Reactive Protein (CRP) Quantitative: Evaluates the presence of inflammation, which can be associated with various types of arthritis. 

  • Rheumatoid Factor (RF): Detects the presence of rheumatoid factor antibodies, often linked to autoimmune diseases like rheumatoid arthritis. 

  • 24-Hour Urine Phosphorus: Evaluates kidney function and mineral metabolism, which can be impacted by certain types of arthritis. 

  • Serum Uric Acid: Crucial for diagnosing gouty arthritis, as elevated uric acid levels are characteristic of this condition.  

Home Collection for Arthritis Profile Test Near You 

Opting for Metropolis Healthcare's home sample collection service for your arthritis profile test provides numerous benefits. A trained phlebotomist will visit your home to collect the necessary blood samples, ensuring both comfort and safety. With Metropolis Healthcare's strict standards for sample handling, you can rest assured that the accuracy of the test will be maintained. You'll also receive timely and reliable results, as Metropolis Healthcare is committed to making healthcare more accessible by delivering high-quality diagnostic services directly to your home. 

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Arthritis Profile Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Arthritis Profile with a clear pricing structure. The Arthritis Profile Price in Mumbai is ₹ 3,230. We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

CBC and Routine Urine Examination is done. Apart from this the Arthritis Profile test measures the ESR, CCP, CRP, ANA, Uric Acid, ASO, RA levels in the blood.

  • To diagnose and assess patients with arthritis.
  • To differentiate between rheumatoid Arthritis [RA] and other types of arthritis based on the laboratory test parameters.
  • It may also be done in certain autoimmune disorders.

People with the following symptoms:

  • Frequent joint pain and stiffness.
  • Severe early morning pain and stiffness [mainly in the small joints of hands and feet]
  • Visible signs of inflammation in the joints.
  • Those with a family history of RA/Arthritis.

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. Urine sample will also be collected.

CBC test

Features of chronic anaemia i.e., low haemoglobin and hematocrit are associated with inflammatory conditions causing arthritis.

ESR test

ESR are elevated in inflammatory conditions causing arthritis.

Urine Examination Routine

Presence of glucose, ketones or proteins indicates further tests for gauging impact of associated autoimmune disease on kidneys. 

RA test

RA factor present or positive (high) usually indicates the diagnosis of rheumatoid arthritis. However, it may also be positive in certain other autoimmune disorders like Systemic lupus erythematosus (SLE), Sjogren's syndrome, mixed connective tissue disorders, inflammatory lung diseases, and certain cancers. The RA factor test may also be positive in certain healthy individuals especially the elderly population. The absence of RA factor or negative (low) RA factor test is used to rule out RA disease. But, some patients with RA may have negative or low RA factor.

CCP Antibody Cyclic Citrullinated Peptide

Detection of anti-CCP antibodies [Positive Result] is used as an aid in the diagnosis of Rheumatoid Arthritis and should be used in conjunction with other clinical information.

Antinuclear Antibodies Test

ANAs [Positive Result] indicate the possible presence of autoimmunity & provide, therefore, an indication of autoimmune illness. A positive result, autoantibodies against any one or in some cases simultaneously against more than one antigens may be present and further monospecific tests or panel of profiles can be used to determine the specific

If the test is negative, detectable level of auto antibodies is ruled out.

All weak positive (+) results may be repeated after 6 - 8 weeks.

ASO test

Elevated levels indicate past history of streptococcal infection (rheumatic fever, scarlet fever, tonsillitis, glomerulonephritis, etc.).

In the case of monoclonal gammopathies (e.g. WAldenstroms macroglobulinaemia) the measurements yield false highly elevated ASL concentrations in some patients.

CRP-C Reactive Protein

Increased CRP-C Reactive Protein levels may indicate infection, tissue injury, inflammatory disorders and associated diseases. Increase in CRP values are non-Specific and should not be interpreted without a complete history.

Uric Acid Serum Test

High levels of uric acid are associated with numerous renal and metabolic disorders i.e., renal failure, gout, leukaemia, psoriasis, starvation or other wasting conditions and subjects receiving cytotoxic drugs

Low levels of uric acid can be seen in liver disease, Renal tubular absorption defects and over treatment of gout.

  • Arthritis Test
  • CCP test
  • CRP test
  • ANA test
  • ASO test
  • RA test
  • Complete blood count (CBC) evaluates cells circulating in blood i.e., red blood cells, white blood cells and platelets which determine general state of heath of an individual. Chronic anaemia is often seen in inflammatory diseases. It is also done to look for acute falls in hematocrit and hemoglobin levels in SLE and Sjogren’s syndrome.
  • If any abnormality is detected, further tests are recommended.

 

This test measures the sedimentation rate of red blood cells. Erythrocyte sedimentation rate (ESR) is a non-specific marker which increases in inflammation, chronic infection, autoimmune diseases, pregnancy, menstruation, hypothyroidism.

  • This test is done to detect any Renal damage due to the associated autoimmune conditions causing arthritis.

RA test is used to detect the presence or absence of RA factor in the blood. RA factor is usually present in Rheumatoid arthritis or even in certain other autoimmune conditions.

This test is used for the semi-quantitative determination of the IgG class of auto antibodies specific to CCP in biological specimens. This test is more specific than RA test for diagnosis rheumatoid arthritis

  • Antinuclear antibodies (ANAs) are unusual antibodies, detectable in the blood, that have the capability of binding to certain structures within the nucleus of the cells. ANAs indicate the possible presence of autoimmunity & provide, therefore, an indication of autoimmune illness.
  • The ANA test is a sensitive screening test used to detect autoimmune diseases.

ASO antibodies are specific antibodies to streptococcal metabolites that provides valuable information regarding past streptococcal infection (rheumatic fever, scarlet fever, tonsillitis, glomerulonephritis, etc.).

Measurement of CRP is useful for the detection and evaluation of infection, tissue injury, inflammatory disorders and associated diseases. Its level are elevated in autoimmune and chronic diseases.

Uric acid is a breakdown product of purine which is a type of protein required in nucleic acid synthesis. This test is done for diagnosis of gout which can also present as arthritis.

The Arthritis Profile test is a comprehensive set of blood tests designed to detect, diagnose, and monitor arthritis. It includes various parameters that help identify the type of arthritis, assess its severity, and track treatment effectiveness.

The Arthritis Profile test is essential for early detection, accurate diagnosis, and effective management of arthritis. It helps identify the specific type of arthritis, assess severity, monitor disease progression, and evaluate treatment effectiveness, ultimately improving patient outcomes.

The Arthritis Profile test includes markers such as ESR, CRP quantitative, serum calcium, 24-hour urine phosphorus, rheumatoid factor (RF), serum urea acid, dihydroxyvitamin D, and a complete blood picture (CBP).

The Arthritis Profile test can be performed at any age, particularly for individuals experiencing arthritis symptoms or with a family history of the condition. There is no specific age limit for this test.

The benefits of the arthritis profile blood test include early detection, accurate diagnosis of arthritis type, assessment of disease severity, monitoring treatment effectiveness, and adjustment of treatment plans as needed, ultimately leading to better patient outcomes.

No, fasting is usually not required before the Arthritis Profile test. However, it's adviseable to confirm with your healthcare provider or the testing lab for any specific instructions.

Yes, Metropolis Healthcare provides home sample collection for Arthritis Profile test. A trained phlebotomist will visit your home to collect the required samples, ensuring both your comfort and convenience while maintaining high-quality testing standards.

The arthritis profile blood test results are typically available within 24 hours post day/time the sample is collected and processed. 

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