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Anaemia Profile-Haemolytic Type

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This profile detects hemolytic type of anemia.

Hemolytic anemia occurs when there are not enough red blood cells in the body. Hemolysis can occur too quickly or too frequently under certain circumstances, such as autoimmune diseases

failing the bone marrow, blood transfusion complications, illnesses hereditary blood disorders like sickle cell anaemia or thalassemia, and a few medications.


Decrease in hemoglobin level or number of red blood cells (RBC) leads to anaemia. This affect oxygen carrying capacity of blood to various tissues and organs. Commonest cause of anemia is nutritional deficiency of iron, vitamin B12 and folic acid. This can be due to either a lack of these substances in the diet, an increased loss that cannot be compensated by diet alone or an increased unmet demand during pregnancy and lactation.


Few of hereditary haemolytic anaemias include Hemoglobinopathies (Thalassemia's, Sickle cell anaemia etc.), enzyme deficiency disorders (G6PD deficiency). Acquired Haemolytic Anaemias like Autoimmune Haemolytic Anaemias, Microangiopathic haemolytic anaemia are also common in Indian population.


Anaemia Profile- Haemolytic Type includes both basic & specialised tests to identify hemolytic anaemia and its causes.


Associated Tests:

A0442    Anaemia Profile-Mini

A0441    Anaemia Profile-Maxi

A0440    Anaemia Profile-Haemolytic Type

A0585    Anaemia Profile - Macrocytic

A0586    Anaemia Profile - Microcytic Hypochromic

A0443    Anaemia Profile-Nutritional

A0444    Anaemia Profile-Pernicious

A0587    Anaemia Workup Profile


Written by : Supriya Kulkarni, Lead-Content & Training




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Anaemia Profile-Haemolytic Type Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Anaemia Profile-Haemolytic Type with a clear pricing structure.

The Anaemia Profile-Haemolytic Type Price in Mumbai is ₹ 3,825 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

This test is for individulas to evaluate hemolytic anemia.

This profile detects hemolytic type of anemia. This profile includes CBC, Reticulocyte Count, G6PD, Osmotic Fragility, Haptoglobulin, Abnormal Hb Studies, LDH, COOMBS Direct,Bilirubin.

  • Anaemia Profile- Haemolytic Type Test is done to diagnose hemolytic anaemia and to identify its causes.
  • Anaemia Profile- Haemolytic Type is done in people who show signs and symptoms of hemolytic anaemia, who do not respond to the treatment for anaemia, in patients with family history of a hereditary anaemia, in pregnant women, in patients with chronic diseases and chronic infections.


You should get the hemolytic anemia test done if you observe the following symptoms:

  • Fatigue
  • Weakness
  • Tiredness
  • Irritability
  • Headache
  • Shortness of breath
  • Patient Preparation: 12-14 hrs fasting required 


    Total Tests Included: 9 (CBC (27 parameters), Reticulocyte Count, G6PD, Osmotic Fragility, Haptoglobulin, Abnormal Hb Studies, LDH, COOMBS Direct, Bilirubin)


    TAT: From DOS 

Anaemia Profile- Haemolytic Type Profile includes the following group and individual test:

  • CBC tests for all Blood cells like RBC, WBC and Platelets, their count and morphology along with Hemoglobin level (Hb), RBC indices (MCV, MCH, MCHC, RDW) & PDW.
  • Reticulocyte count is useful in monitoring treatment in anaemic patients and also to know the bone marrow activity. CRP, TSH and Creatinine are essential to diagnose anaemias due to Chronic Diseases and Infections.
  • LDH is found in red blood cells, and hemolysis releases it into the bloodstream.
  • Bilirubin, a by-product of haemoglobin breakdown, rises as haemoglobin is released. In hemolysis, indirect hyperbilirubinemia is frequently observed.
  • Haemolytic Anaemias are diagnosed by tests like Haptoglobin, Osmotic Fragility, Direct Coombs Test, G6PD and abnormal hemoglobin studies (for hemoglobinopathies).

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.


As per WHO, women with Hb < 12mg/dL & men with Hb <13mg/dL are considered anaemic.

  • In hemolytic anaemia, Hb, serum Iron, ferritin levels, transferrin saturation are low and TIBC level is high.
  • In anaemia of chronic disease Hb, serum Iron, transferrin saturation, TIBC are low with high ferritin.
  • In hemolytic anemia, bilirubin and LDH are elevated.
  • Investigations like G6PD, Haptoglobin, Osmotic Fragility, DCT are abnormal in Haemolytic Anaemia.
  • Abnormal Hb studies can detect Sickle cell & Thalassemia.
  • CRP when high indicates Infection and Inflammation.
  • Creatinine if increased indicates abnormality in kidney function.


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