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3-Methyl Histidine Quantitative Urine Test

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3-Methyl Histidine is an amino acid found in skeletal muscle. The breakdown product of this amino acid, methylhistidine, is excreted into the urine. 3-Methyl Histidine is often used as a diagnostic marker of muscle protein degradation.

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3-Methyl Histidine Quantitative Urine Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the 3-Methyl Histidine Quantitative Urine Test with a clear pricing structure.

The 3-Methyl Histidine Quantitative Urine Test Price in Mumbai is ₹ 6,570 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

This test measures the levels of a breakdown product of the amino acid 3-Methyl Histidine in the urine. 

Doctors will recommend this test to

  • To investigate the cause of muscle weakness or wasting.
  • To diagnose conditions that cause muscle damage.
  • To monitor treatment effectiveness for muscular dystrophy and other muscle diseases.

Your doctor might recommend this test if you have

  • Symptoms suggestive of muscular dystrophy, kidney disease or rhabdomyolysis.
  • Family history or genetic risk factors for muscular dystrophy, kidney disease or rhabdomyolysis.
  • Unexplained muscle wasting or weakness.
  • Symptoms suggestive of other kidney diseases.

Elevated levels of 3-Methyl Histidine in urine can indicate muscle tissue damage or breakdown due to certain diseases, including muscular dystrophy, rhabdomyolysis, and kidney disease. Level also increases in polymyositis, thyrotoxic myopathy while the level falls significantly in hypothyroid myopathy.

During the test, you will be asked to provide a spot urine sample to be sent to the laboratory for testing.

To prepare for this test

  • Your doctor may advise you not to take certain medications that can interfere with the test results.
  • Drink plenty of fluids, but avoid excessive exercise or muscle strain before the test.

Please reach out to your healthcare provider for any specific requirements.

Other tests that may be ordered alongside the 3-Methyl Histidine Quantitative Urine test include:

  • Creatinine Blood Test: This measures levels of creatinine, which is a waste product excreted by the kidneys.
  • CK (Creatine Kinase) Blood Test: This measures levels of an enzyme that is released when there is muscle damage.

Other blood tests or imaging tests may also be ordered depending on individual cases.

Urinary methylhistidine, methylhistidine quantitative urine

Rhabdomyolysis is a condition where muscle tissue breaks down quickly and releases its contents into the bloodstream, leading to potential complications such as renal failure, cardiac arrhythmias, and death. Causes of rhabdomyolysis include trauma, infections, alcohol abuse, and certain medications.

Muscular dystrophy encompasses a collection of over 30 genetic disorders characterized by the gradual weakening and deterioration of voluntary movement-associated skeletal muscles, with variations in age of onset, muscle involvement, and severity.

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