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17-Hydroxyprogesterone (17-OH Progesterone) Test
Also known as: 17-Hydroxyprogesterone/ 17-OH Progesterone Test
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
17-Hydroxyprogesterone/ 17-OH Progesterone Test Details in Brief
| Also Known As | 17-OHP Test, 17 Alpha Hydroxyprogesterone Test, Hydroxyprogesterone Blood Test |
|---|---|
| Purpose | Helps diagnose congenital adrenal hyperplasia (CAH) and assess adrenal gland function and hormone balance |
| Preparation | Early morning sample preferred (between 8–10 AM) |
| Fasting | Fasting not required |
| Reporting Time | Next day |
| Cost | 1,800 |
What is a 17-Hydroxyprogesterone (17-OH Progesterone) Test?
The 17-Hydroxyprogesterone (17-OHP) Test measures the amount of 17-hydroxyprogesterone, a hormone made by your adrenal glands, in your blood. This hormone plays an essential role in producing cortisol and other vital steroids. The test helps detect Congenital Adrenal Hyperplasia (CAH), a genetic condition in which the adrenal glands do not make enough cortisol and produce excess androgens instead.
It is also used to assess hormone-related issues such as infertility, irregular menstrual cycles, or early puberty. The test requires a simple blood sample drawn from a vein in your arm.
What Does a 17-Hydroxyprogesterone (17-OH Progesterone) Test Measure?
The test evaluates the level of 17-hydroxyprogesterone in your blood, helping to:
- Diagnose Congenital Adrenal Hyperplasia (CAH): Detects enzyme deficiencies affecting cortisol synthesis.
- Assess Adrenal Function: Determines how well your adrenal glands are producing essential hormones.
- Monitor Hormone Balance: Identifies abnormal androgen or cortisol production levels.
- Evaluate Reproductive Disorders: Helps investigate menstrual irregularities, infertility, and early puberty in children.
- Monitor Treatment Response: Used to track effectiveness of hormone replacement therapy in CAH patients.
17-Hydroxyprogesterone (17-OH Progesterone) Test: Who Needs It and Why It’s Done
What Symptoms May Call for a 17-Hydroxyprogesterone (17-OH Progesterone) Test?
You may be advised to undergo this test if you experience:
- Early puberty (in boys) or excessive body hair (in girls)
- Irregular or absent menstrual cycles
- Ambiguous genitalia in newborns
- Persistent fatigue, dehydration, or salt loss
- Symptoms of adrenal insufficiency such as low blood pressure or weakness
Who Should Get a 17-Hydroxyprogesterone (17-OH Progesterone) Test?
This test is especially useful for:
- Newborns: Routine screening to detect CAH early.
- Children/Adolescents: With signs of hormonal imbalance or early puberty.
- Adults: Women with infertility, irregular periods, or signs of excess androgen (e.g., acne, hirsutism).
- Patients under treatment: To monitor response to therapy for CAH or other adrenal disorders.
Why is a 17-Hydroxyprogesterone (17-OH Progesterone) Test Done?
The test is primarily done to detect or confirm congenital adrenal hyperplasia and evaluate adrenal function. It can also help distinguish adrenal from ovarian causes of hormonal imbalance.
Importance of a 17-Hydroxyprogesterone (17-OH Progesterone) Test
This test is a vital part of endocrine evaluation, especially in newborns and women with hormone imbalance symptoms. Early diagnosis of CAH enables timely treatment to prevent serious complications like dehydration, abnormal sexual development, or infertility. Monitoring 17-OHP levels helps ensure treatment effectiveness and long-term hormonal stability.
17-Hydroxyprogesterone (17-OH Progesterone) Test Booking & Reports – Metropolis Healthcare
How to Book the 17-Hydroxyprogesterone (17-OH Progesterone) Test and Get Your Reports?
- Simple Online Booking
Schedule your test through the Metropolis Healthcare App or website. Select the 17-Hydroxyprogesterone (17-OH Progesterone) Test, choose a convenient time, and provide your address for home sample collection. You may also visit your nearest Metropolis Lab. - Safe Home Sample Collection
Our skilled phlebotomists visit your home, ensuring hygienic and painless blood sample collection. - Sample Tracking Updates
Track your sample in real-time through the Metropolis Healthcare website for transparency at every stage. - Accurate Laboratory Testing
Your sample is processed in NABL & CAP accredited laboratories using advanced CLIA technology for precise and reliable results. - Quick & Easy Reports
Get your reports via email, WhatsApp, or download them directly from the Metropolis website or app.
Is Home Sample Collection for 17-Hydroxyprogesterone (17-OH Progesterone) Test Available Near You?
Yes, Metropolis Healthcare provides doorstep sample collection with trained professionals following strict safety and hygiene standards. This service ensures comfort and convenience, especially for children or bedridden patients.
How Long Does It Take to Get a 17-Hydroxyprogesterone (17-OH Progesterone) Test Report?
Reports are usually available the next day once your sample reaches the lab.
Note: Reporting time may vary based on your location.
Where Can I See or Get 17-Hydroxyprogesterone (17-OH Progesterone) Test Results?
You can access your test reports easily via the Metropolis website or app using your registered login details. Reports are also shared via email and WhatsApp, and you may collect a printed copy from the nearest lab if desired.
Interpreting 17-Hydroxyprogesterone (17-OH Progesterone) Test Results
What Your 17-Hydroxyprogesterone (17-OH Progesterone) Test Results May Indicate
|
Parameter |
Normal Range |
High Values May Indicate |
Low Values May Indicate |
|
17-Hydroxyprogesterone |
Depends on age and menstrual phase |
Congenital Adrenal Hyperplasia (CAH), adrenal tumour, or hyperandrogenism |
Adrenal insufficiency or reduced cortisol production |
Understanding Abnormal 17-Hydroxyprogesterone (17-OH Progesterone) Test Results by Parameter
|
Parameter |
High Values May Indicate |
Remarks |
|
17-Hydroxyprogesterone |
Classic or Non-classic Congenital Adrenal Hyperplasia (CAH), adrenal tumours, ovarian hyperandrogenism |
Levels vary by age, gender, and menstrual phase. Morning collection ensures accuracy. |
How Should You Prepare for a 17-Hydroxyprogesterone (17-OH Progesterone) Test?
Proper preparation helps ensure reliable results:
- Fasting not required: You can eat and drink normally before the test.
- Early morning sample: Adults should ideally have the test between 8:00 AM and 10:00 AM.
- Cycle timing for women: Your doctor may advise testing during specific phases of your menstrual cycle.
- Medication disclosure: Inform your doctor if you’re taking corticosteroids or birth control pills, as they may influence results.
- Avoid alcohol and nicotine: Refrain from consuming these for at least 24 hours before testing.
- Stay hydrated: Normal hydration helps ensure a smoother blood draw.
How Is a 17-Hydroxyprogesterone (17-OH Progesterone) Test Done? (Step-by-Step Procedure)
- Preparation: You’ll be seated comfortably, and an elastic band is tied around your upper arm.
- Cleaning: The site is disinfected with antiseptic.
- Blood Draw: A sterile needle is inserted into a vein in your arm to draw the sample.
- Sample Collection: Around 2 ml of blood is collected in a gel vacutainer tube.
- Completion: The needle is removed, and a small bandage is applied.
- Processing: The sample is analysed using Chemiluminescence Immunoassay (CLIA) technology in the laboratory.
Conditions That May Affect 17-Hydroxyprogesterone (17-OH Progesterone) Test Accuracy
Some factors can influence your test results:
- Timing: 17-OHP levels vary throughout the day; morning testing is recommended.
- Medications: Corticosteroids, oral contraceptives, or hormonal therapy can affect readings.
- Age and gender: Reference values differ across age groups and reproductive stages.
- Illness or stress: Severe illness or stress may alter hormone levels temporarily.
- Premature infants: May show naturally high 17-OHP due to immature adrenal function.
Diseases That a 17-Hydroxyprogesterone (17-OH Progesterone) Test Can Help Detect
This test can help diagnose or monitor:
- Congenital Adrenal Hyperplasia (CAH)
- Adrenal gland tumours
- Ovarian or testicular disorders
- Hormone imbalance conditions (hyperandrogenism)
- Adrenal insufficiency
17-Hydroxyprogesterone (17-OH Progesterone) Test Price in Different Cities
The cost of a 17-Hydroxyprogesterone (17-OH Progesterone) Test may vary depending on your location. Here's a table showing the approximate price range for the 17-Hydroxyprogesterone (17-OH Progesterone) Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 1550 to ₹ 1850 |
|
|
₹ 1550 to ₹ 1850 |
|
|
₹ 1550 to ₹ 1850 |
|
|
₹ 1550 to ₹ 1850 |
The 17-Hydroxyprogesterone (17-OH Progesterone) Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive 17-Hydroxyprogesterone (17-OH Progesterone) Test prices across major cities in India.
References
- Speiser P.W., et al. (2018). Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: An Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology & Metabolism, 103(11), 4043–4088. PMID: 30336124
- Witchel S.F., et al. (2019). Classic and non-classic congenital adrenal hyperplasia. Endocrine Development, 36, 51–63. PMID: 31416991
- Han T.S., et al. (2017). Diagnosis and management of congenital adrenal hyperplasia. BMJ, 358, j3954. PMID: 28851795
- El-Maouche D., et al. (2017). Congenital adrenal hyperplasia. Lancet, 390(10108), 2194–2210. PMID: 28919209
- Turcu A.F., et al. (2020). Adrenal steroidogenesis and congenital adrenal hyperplasia. Endocrinology and Metabolism Clinics of North America, 49(3), 367–386. PMID: 32800628
17-Hydroxyprogesterone/ 17-OH Progesterone Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the 17-Hydroxyprogesterone/ 17-OH Progesterone Test with a clear pricing structure.
The 17-Hydroxyprogesterone/ 17-OH Progesterone Test Price in Mumbai is ₹ 1,800 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
It measures 17-hydroxyprogesterone levels to detect congenital adrenal hyperplasia or other adrenal hormone disorders.
The sample should ideally be collected early in the morning between 8:00 AM and 10:00 AM for accurate results.
Fasting is not required for this test unless your doctor has ordered additional fasting-based tests.
Yes, oral contraceptives and corticosteroids can reduce 17-OHP levels and should be discussed with your doctor before testing.
Elevated levels may indicate congenital adrenal hyperplasia, adrenal tumours, or increased androgen production.
Yes, it helps identify abnormal hormone activity leading to early puberty or ambiguous genital development.
A healthcare professional collects a blood sample from a vein in your arm, which is analysed using CLIA technology.
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