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T4 Total and Free in Pondichery



There are two separate tests under T4 titled Total and Free. Both these tests evaluate how well the thyroid gland is functioning. These two tests have been the go-to test for many physicians for diagnosing Hyper and Hypothyroidism.

T4 exists in 2 forms in the blood – Bound to a protein and free. The Free T4 is available for use by the body and tissues. However, most of the T4 present in the blood is bonded to a protein. The body is able to use the free T4 and hence the free T4 test is an important test to evaluate how well your thyroid gland is functioning.

The free T4 is the active form and hence measuring this i.e. the T4 Free test is considered to be more accurate and insightful

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    Your doctor may order the T4 test if he suspects that you may have one of the following thyroid problems

    • hyperthyroidism, or overactive thyroid
    • hypothyroidism, or underactive thyroid
    • hypopituitarism, or underactive pituitary gland

    Symptoms like change in blood pressure, heart rate, hand tremors, anxiety, sleeplessness, sudden unexplained changes in weight, intolerance to cold or even sensitivity to light. Some women face menstrual irregularities due to thyroid disorders and the thyroid test may be ordered along with other hormonal tests.

The T4 test is ordered if a thyroid disorder is suspected. A T3 test and a TSH test may be ordered along with T3 test to understand underlying problems. These three tests put together comprise a Thyroid profile test.

A T4 total or free test is usually ordered in combination with TSH or if a previously conducted TSH test records an abnormality. These tests are performed when a patient presents symptom of Hyperthyroidism or Hypothyroidism.

Reference Values

Normal level (T4): 4.6-12 ug/dl


A result below normal range indicates that the thyroid gland is underactive and hypothyroidism results. A result above normal range indicates an overactive thyroid gland and hyperthyroidism.

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T4 Total and Free