SHBG Sex Hormone Binding Globulin Serum in Mumbai - Metropolis Healthcare
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SHBG Sex Hormone Binding Globulin Serum in Mumbai

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The SHBG test measures the amount of SHBG in the blood

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    The test is most commonly conducted to evaluate low testosterone in men and also used in evaluating the signs of excess androgens in women.

Your doctor would recommend this test for you if he notices the signs of low testosterone. The symptoms are:

  1. Infertility
  2. Low Sex Drive
  3. Erectile Dysfunction (in men)
  4. Irregular Menstrual Cycle (in women)
  5. Excess facial and body hair (in women)

This test is not ordered that frequently.

Sex hormone binding globulin (SHBG) is a protein produced by the liver that transports the hormones testosterone which is an androgen, dihydrotestosterone (DHT) also an androgen, and estradiol which is an estrogen in the blood as which are traditionally, inactive. Modulations in SHBG levels can affect the amount of hormone that is available to be utilised by the body's tissues.

About 45 to 60 per cent of testosterone in blood normally amount to SHBG in men and only 2 to 3 per cent of testosterone is readily available to use.  While in women, SHBG plays a critical role in regulating the levels of androgens and estrogens circulating throughout the body.

If your SHBG level is not normal, it can affect the level of hormones in men and women leading to concerns like infertility, erectile dysfunction and irregular periods.

Reference Values Of SHBG Sex Hormone Binding Globulin Serum

The normal ranges for SHBG concentrations in adults are:

  • Males:10 to 57 nanomoles per liter (nmol/L)
  • Females (nonpregnant):18 to 144 nmol/L

 

Interpretations

A high SHBG level shows that less testosterone is available for usage and low SHBG means more total testosterone is available. 

Increased SHBG levels may indicate:

  • Liver disease
  • Hyperthyroidism
  • Anorexia
  • Hypogonadism
  • Pregnancy

 

Decreased SHBG level indicate:

  • Type 2 diabetes, Obesity
  • PCOS
  • Hypothyroidism

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SHBG Sex Hormone Binding Globulin Serum

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