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Interferon gamma release assay

2700

2700

Interferon gamma release assay test is used to diagnose Tuberculosis.

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    To diagnose tuberculosis infection

Your doctor may recommend this test for you if he suspects that you have tuberculosis.

The symptoms include:

  • An exposure to a person with tuberculosis is considered a risk factor
  • chroniccough that produces phlegm or sputum, sometimes blood – a cough that persists more than two weeks and worsens over a period of time
  • fever
  • chills
  • night sweats
  • unexplained weight loss

Interferon-release assays (IGRAs) represents the advances in tuberculosis immunology and evolutionary biology. IGRAs were intended to replace tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection because of their logistical advantages and enhanced specificity over TST.

Reference Values

A positive result is associated with an increased risk for current or future active tuberculosis

Interpretations

Neither IGRAs nor the TST are accurately predictive markers of active TB infection, however, use of IGRAs in some populations might reduce the number of people considered for preventive treatment. Until better predictive markers are in place and instead of solely relying on predictive ability of the tests, several tests for detecting latent tuberculosis should be selected on the basis of relative specificity in different populations, logistics, cost, and preferences of the patients.

 

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Interferon gamma release assay

2700