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Immunofixation-quantitative Serum

5600

5600

The immunofixation blood test is used to identify proteins called immunoglobulins in blood.

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    An immunofixation blood test, also known as protein electrophoresis, measures certain proteins in the blood. Proteins play vital role in providing energy for the body, rebuilding muscles, and providing support to the immune system. There are two main types of proteins in the blood: albumin and globulin. The test distinguishes these proteins into subgroups based on their size and electrical charge. Measuring the proteins in each subgroup can help early diagnosis of a variety of diseases

Your doctor may recommend this test for you if he sees the signs of multiple myeloma or Waldenstrom’s macroglobulinemia. The symptoms include:

  • bone pain in the back or near the ribs
  • weakness and fatigue
  • sudden weight loss
  • weak bones
  • recurrent infections
  • weakness in the legs
  • nausea and vomiting

Immunoglobulins (Ig) are also known as antibodies. These proteins help protect the body against critical disease. There are various types of Immunoglobulins. Certain illnesses result in the growth of an excess number of antibody-producing cells. In some conditions, these cells can produce a large number of antibodies that are all exactly the same. These are known as monoclonal antibodies. In a serum immunofixation (IFX) test, they appear as a spike called an M spike which are considered to be abnormal Ig. The IFX test also helps identify the type of abnormal Ig present. This information can be helpful in establishing a diagnosis.

Reference Values

Normal values of total protein for children are:

  • Premature infants: 4.2 to 7.6 g/dL
  • New-borns: 4.6 to 7.4 g/dL
  • Infants: 6 to 6.7 g/dL
  • Children: 6.2 to 8 g/dL

 

Normal ranges for albumin in children are:

  • Premature infants: 3 to 4.2 g/dL
  • New-borns: 3.5 to 5.4 g/dL
  • Infants: 4.4 to 5.4 g/dL
  • Children: 4 to 5.9 g/dL

Interpretations

If your results show that you have monoclonal proteins, known as the M-proteins, it might mean that you have multiple myeloma. You will need other tests to confirm your results.

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Immunofixation-quantitative Serum

5600