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LP PLA2 (PLAC) Test

2500

2500

A LP PLA2 (PLAC) test measures the amount of lipoprotein- associated phospholipase (Lp-PLA2) in blood. 

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    PLAC test is a simple biopsy that assesses your cardiac health. Cholesterol testing alone may fall short to detect a definitive diagnosis and cholesterol test can miss hidden risks for heart attack. Around 50% of heart attacks occur in patients with normal cholesterol; rather most cardiovascular (CV) events i.e., heart attack and strokes are caused due to rupture of plaque that is formed by cholesterol deposition within the blood vessels.

    In heart diseases, it's known that an unhealthy lifestyle-such as intake of fatty foods, excess alcohol and smoking have a significant role to play in developing the risk of a stroke. This can shoot up cholesterol levels and increases blood pressure. Blood vessels become clogged with fatty deposits which will dislodge and make their route to the brain, depriving it of oxygen. Despite the fact, the doctors still opine that significant number of events occur in people with no obvious risk factors for the disease, hence measuring these levels is critical. 
    Eventually, the unstable plaque can rupture, become potential lethal clots and debris loose in bloodstream—causing a stroke or a heart attack . PLAC test is second generation enzyme linked immunoassay test, helping doctors with prediction of future strokes and heart attack

Your doctor would recommend this test for you if he suspects the risks of cardiovascular diseases or a chance of stroke based on your family history, age, cholesterol levels.

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a blood vessel enzyme, found to be the second most predictive of heart attack risk, also gives indications of plaque that could abruptly precipitate like a volcano. The higher the level of Lp-PLA2, correlates to the corresponding higher risk of cardiac events i.e., heart attack and stroke - even with normal LDL cholesterol.

Reference Values

Low Risk: Less than 152 nmol/min/ml

Medium Risk: 152 – 194 nmol/min/ml

High Risk: 195 – 400 nmol/min/ml

 

Interpretations

Patients with medium and high risk should be immediately managed with lifestyle modifications and medications. PLAC test is only a screening test and can predict your chances of falling prey to heart attack and stroke. A positive result and presence of high levels should be monitored, and followed-up with additional diagnostic and medication strategies in order to effectively manage the condition and prevent the occurrence of cardiac events in future.

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LP PLA2 (PLAC) Test

2500