The body immune system produces antibodies - proteins that are critical for fighting and clearing out the virus.
Introduction: SARS CoV 2 is an enveloped, single-stranded RNA virus of the family Coronaviridae, genus Beta coronaviruses.
SARS CoV 2 is transmitted person-to-person primarily via respiratory droplets, but also indirect transmission through contaminated surfaces is possible.
SARS CoV 2 can be isolated from respiratory samples obtained via naso/oropharyngeal swabs or from sputum. The virus accesses host cells via the angiotensin-converting enzyme 2 (ACE2), which is the most abundant in the lungs.
The incubation period for COVID 19 is thought to range from 2 14 days following exposure, with most cases showing symptoms approximately 4 5 days after exposure.
Definite COVID 19 diagnosis entails SARS CoV 2 detection by RT PCR method
Antibody to SARS CoV 2 is an immunoassay test for qualitative detection of antibodies (including IgG) to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2).
Seroconversion or recovery is observed after a median of 10 13 days after symptom onset for IgM and 12 14 days for IgG and last for several months. Levels and chronological order of IgM and IgG antibody appearance are highly variable supporting detection of both antibodies simultaneously.