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kidney cancer treatment

What is Kidney Disease? All You Need To Know

Introduction Chronic kidney diseases affect around 10% of the Indian population. Statistics show that close to 1 lakh cases of renal failure are reported every year. Kidney disease results from kidney damage, making them unable to carry out their functions. This damage can be caused due to high blood pressure, diabetes or other long-term health conditions. Kidney disease can also lead to other health problems, such as nerve damage, weak bones and malnutrition. What is kidney disease? Kidneys are the organs responsible for regulating your body’s pH levels, salt, potassium, and various functions. They are two bean-shaped organs that are usually the size of your fists. Your kidneys carry out three main functions: filtering excess water and waste out of the blood and creating urine. Kidney disease results from kidney damage, making it difficult for them to filter the blood as they should. Here you will understand more about the function of the kidneys and the causes, symptoms, types and treatment of kidney disease. The longer you wait before treating this condition, the more chances it may result in total renal failure. In this case, you would need to undergo dialysis, a form of treatment that helps filter and purify your blood with the help of a machine. As there is no known cure for kidney failure, the individual will have to undergo dialysis for the rest of their life. Types and causes of kidney disease Here is a comprehensive kidney disease list that describes the different types and causes of kidney diseases so that you know the risk and the mode of action required for such conditions. Chronic kidney disease This is one of the most common types of kidney disease. It is a long-term condition that does not improve over time and can result from high blood pressure. This happens because of the pressure applied on the glomeruli (a network of tiny blood vessels in the kidneys that helps purify the blood). Over a period, the increased pressure on these can cause damage to these vessels, which in turn limits kidney function. Ultimately the kidney function declines to the point where the kidneys cannot carry out their function correctly, causing the individual to need dialysis and, in more severe cases, a kidney transplant. Diabetes is another major cause of chronic kidney disease. In this case, the increased sugar level in the blood causes the blood vessels in the kidneys to get damaged over time. The kidneys cannot clean the blood properly, so the body can get overloaded with various toxins. Kidney stones Another common problem is the presence of kidney stones. This disease occurs because substances like minerals crystallise in the kidneys and form solid masses, also known as stones. When urinating, these stones are often dispelled from the body, but the process can be significantly painful. Polycystic kidney disease This genetic disorder often results in the growth of multiple tiny sacs of fluid known as cysts in the kidneys. These cysts can interfere with the kidneys' optimum functioning, resulting in kidney failure. Note that individual kidney cysts are relatively common among individuals and can be harmless. It is only polycystic kidney disease that can be life-threatening. Glomerulonephritis Glomerulonephritis is a kidney disease in which the glomeruli get inflamed. This is usually caused due to drugs, infections or congenital abnormalities. It usually gets better on its own. Urinary tract infections Urinary tract infections are caused because of bacterial infections in the urinary system. This kind of infection is usually seen in the urethra or bladder. They are easy to treat but, if left untreated, can also cause kidney disease. symptoms of Kidney disease Kidney diseases may go unnoticed as their symptoms are less noticeable than other diseases. However, if left without treatment, it can have severe consequences. Here are a few early kidney disease symptoms. Fatigue Trouble sleeping Muscle cramps Dry and scaly skin Swelling in ankles and feet Poor appetite Morning puffiness around the eyes Frequent urination Difficulty concentrating Severe kidney disease symptoms may include: Nausea Vomiting Changes in the output of urine A sudden rise in your potassium levels Pericardium inflammation Decrease in sex drive Fluid retention Anaemia Treatment for kidney disease Treatment for any kidney disease involves trying to control the underlying cause of the disease. The treatment options include: Medications Your doctor might prescribe several medications in the case of kidney disease based on the cause, these include: Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers help lower blood pressure A phosphate if your kidneys are having trouble eliminating phosphate A diuretic to eliminate the excess fluid build-up Medicines that help reduce cholesterol levels Vitamin D and calcitriol for bone preservation Erythropoietin helps build red blood cells in patients with anaemia Changes in diet and lifestyle Those with reduced kidney function need to preserve the remaining function so that it can last for longer. Here are a few diet and lifestyle changes you will have to make in your diet and lifestyle Make regular doctor visits Manage your blood sugar levels in case of diabetes Avoid the consumption of painkillers as other non-essential medicines Choose a kidney-friendly diet with limited proteins, sodium and potassium Be more active Don't smoke Try and remain at a weight that is healthy for you Dialysis As there is no known cure for kidney disease your healthcare provider will suggest dialysis when you are in the end stages of kidney disease. There are two main types of dialysis: Hemodialysis: In this case, the blood is circulated through a device that helps get rid of excess waste products before the blood is sent back to the body. Peritoneal dialysis: Here a dialysis solution is placed directly into the abdomen with the help of a catheter. This solution absorbs the waste and can be removed using the same catheter before adding a fresh solution. Book Kidney Function Test Conclusion The kidneys carry out the essential job of waste and excess fluid from the body. When your kidneys stop functioning optimally, they can cause several health issues. Regular health checkups and blood tests help to keep track of your health. You should go the extra mile to get blood and urine tests done if you suspect you may have kidney disease. Metropolis Labs helps their customers with at-home sample collection so that you can keep up with your health from the comfort of your home. Metropolis Healthcare assures accurate results within 48 hours of sample collection. Check out the entire list of diagnostic tests provided to find the ones you need.

kidney cancer treatment

Kidney Cancers: Symptoms, Diagnosis and Treatment

Kidney cancers are predominantly a disease of old age with most patients diagnosed beyond 60 years of age. Kidneys are a pair of excretory organs located in the abdomen. Apart from their role in removal of toxic metabolic by products from the body they are also critical in maintaining the body electrolyte levels and blood pressure. Who may get it? The disease is seen to be related with carcinogenic exposure like smoking and is frequent in people employed in the dry cleaning industry having exposure with gasoline, solvents and heavy metals. The risk is also high among obese and hypertensive patients with long history of exposure to diuretic therapy and NSAIDs (pain killers). Apart from this patients with other benign kidney diseases and those having prolonged history of dialysis are also at increased risk of developing kidney cancers. As per some experts, the risk of Kidney Cancer is gradually growing due to a change in lifestyle and unhealthy food habits in urban cities.   Symptoms of Kidney Cancer Kidney cancers are most commonly localised to the kidney at diagnosis however they have a potential for spread via blood and lymph to various organs with lungs, bone, brain and liver being the most common sites of spread. Classically patients with localised kidney cancers present with symptoms of flank mass, pain and bleeding with urination. In a person presenting with cancer being spread to other organs (metastatic disease), the symptoms may vary from persistent pain in back to headache, vomiting, blurring of vision, seizures and difficulty in breathing.   Diagnosis of Kidney Cancer Usually, a physical examination along with medical history can provide a lot of information to your doctor. He or she will enquire about signs of kidney cancer and other health problems. Many times, an abnormal lump is felt when the doctor examines the belly. Most patients are diagnosed with the help of radiological imaging tests which require use of pre and post contrast CT and MRI images. Kidney biopsy and non-contrast Diffusion weighted MRI are useful in certain clinical scenarios. While most patients with radiological enhancement are correctly diagnosed as kidney cancers, as many as 20% of them are wrongly diagnosed making radiological diagnosis unreliable. Doctors usually recommend a complete blood count for preliminary investigations. People with kidney cancer can have anemia (having too few red blood cells) very commonly, some may have too many red blood cells (called polycythemia) as well. Other lab tests include kidney function and urine analysis. These results become important for further imaging tests or if surgery is planned. The most common benign kidney lesions confused with malignant disease radiologically are fat containing lesions of the kidney. While increasing tumor size on radiological imaging increases the likelihood of kidney cancer, a certain diagnosis requires kidney biopsy. It is majorly done for a certain group of people, those having advanced kidney cancer where the tumor has already spread.   Treatment of Kidney Cancer Fortunately, most kidney cancers are diagnosed as localised disease as small renal masses. Historically these localised kidney cancers were treated with radical nephrectomy which required complete removal of kidneys but recently the treatment guidelines have evolved with acceptance for partial nephrectomy as well as active surveillance in selected patients. Partial nephrectomy requires complete removal of the tumor with maximum preservation of normal functioning kidney tissue on the affected side. For larger localised kidney cancers where complete removal of tumor anyway results in unacceptable residual functioning of kidneys on the affected side, the radical nephrectomy is preferred over partial nephrectomy. Generally localised tumors beyond 7 cms are considered unsuitable for kidney preservation via partial nephrectomy. For advanced metastatic disease, maximum removal of tumor tissues via nephrectomy and even removal of tumor from metastatic sites followed by systemic therapy is an accepted approach. Kidney cancer is a very vascular tumor and hence most systemic therapy in kidney cancers are targeted to block the generation of new blood vessels which are required for facilitating spread of kidney cancer. Overall localised kidney cancers have good prognosis post treatment however for metastatic disease prognosis depends on factors like general well being of the patient, anaemia, high blood calcium and high blood WBC & platelet cell counts at the time of diagnosis. After treatment, it is advised to visit and consult your doctor for follow-up check ups or routine examinations.  

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